Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 7/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383378 | 0.86 | ACACB (0.42) | POLBKMT2AACACBMAPT | |
| SCHEMBL7376074 | 0.81 | CA1 (0.43) | PARP10ALDH1A1MAPT | |
| SCHEMBL7384542 | 0.79 | LMNA (0.47) | POLBKMT2APARP10ALDH1A1MAPT | |
| SCHEMBL7376687 | 0.77 | ACACB (0.37) | POLBKMT2AALDH1A1ACACBMAPT | |
| SCHEMBL7381291 | 0.76 | L3MBTL1 (0.46) | KMT2AALDH1A1ACACBMAPTKDM4E | |
| SCHEMBL254515 | 0.75 | ALDH1A1 (0.37) | POLBKMT2AALDH1A1MAPTNLRP1 | |
| SCHEMBL7382446 | 0.75 | CA2 (0.36) | KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9233400 | 0.73 | ALDH1A3 (0.38) | POLBKMT2APARP10ALDH1A1GLA | |
| SCHEMBL8497023 | 0.73 | MTNR1A (0.37) | KMT2A | |
| SCHEMBL2786249 | 0.73 | ALDH1A3 (0.47) | POLBKMT2APARP10ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889866-A | CARDIOVASCULAR DISEASES, HYPOTENSIVE AGENTS, CONGESTIVE HEART FAILURE | SYNTEX (U.S.A.) INC. (US) | 1989-12-26 | — | — | US | disclosed |