SCHEMBL7385255

SCHEMBL7385255

[CH](NCc1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.58
ADH1C P00326 1/20 0.58
ADH1A P07327 1/20 0.58
ADH7 P40394 1/20 0.58
KMT2A Q03164 3/20 0.46
IDO1 P14902 2/20 0.46
MEN1 O00255 2/20 0.46
THRB P10828 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 4/20 0.44
CYP3A4 P08684 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
ALOX12 P18054 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5539505 0.86 LMNA (0.50) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL5546127 0.86 ADH1B (0.44) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL5534736 0.86 PLA2G1B (0.49) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL5544677 0.86 L3MBTL1 (0.45) ADH1BADH1CADH1AADH7TDP1
SCHEMBL5542584 0.86 SMN1; SMN2 (0.49) ADH1BADH1CADH1AADH7KMT2A
SCHEMBL5545644 0.82 ACHE (0.48) ADH1BADH1CADH1AADH7IDO1
SCHEMBL5541612 0.81 KDM1A (0.47) ADH1BADH1CADH1AADH7IDO1
SCHEMBL5541903 0.81 IDO1 (0.41) ADH1BADH1CADH1AADH7IDO1
SCHEMBL5536817 0.81 NFE2L2 (0.47) IDO1MAPTMAOAPOLB
SCHEMBL5537515 0.81 RAB9A (0.48) ADH1BADH1CADH1AADH7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994896-A1 SULFONYLATED DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 Elan Pharmaceuticals, Inc. (US) 2000-04-26 EP claimed
WO-1999006437-A1 SULFONYLATED DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS INC. (US) 1999-02-11 WO claimed
WO-1995011681-A1 HUMAN ADENOSINE RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-05-04 WO claimed
US-6015789-A LUTEINIZING HORMONE RELEASING HORMONE AGONIST AND A LUTEINIZING HORMONE RELEASING HORMONE ANTAGONIST IN COMBINATION, TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-01-18 US disclosed
WO-1995011681-A1 HUMAN ADENOSINE RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-05-04 WO disclosed