Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400029 | 0.88 | HRH4 (0.58) | CYP3A4CYP2D6CYP2C19HRH4ALDH1A1 | |
| SCHEMBL5496491 | 0.85 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL27874903 | 0.85 | MMP8 (0.67) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL5496496 | 0.85 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL27546532 | 0.85 | LAP3 (0.64) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL7361284 | 0.85 | LAP3 (0.64) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL9560816 | 0.84 | ALDH1A1 (0.50) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL28801052 | 0.84 | MMP8 (0.58) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| Hydrochloric Acid SCHEMBL7350887 | 0.84 | LAP3 (0.62) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL5495922 | 0.82 | GPR142 (0.52) | CYP3A4CYP2D6CYP2C19MMP8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853476-A | Phosphorus containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |