Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386752 | 0.84 | CYP3A4 (0.51) | ALDH1A1CYP3A4CYP2D6CYP2C19PPID | |
| SCHEMBL5496496 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19PPIDMMP8 | |
| SCHEMBL27874903 | 0.83 | MMP8 (0.67) | ALDH1A1CYP3A4CYP2D6CYP2C19PPID | |
| SCHEMBL5496491 | 0.83 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19PPIDMMP8 | |
| SCHEMBL28801052 | 0.82 | MMP8 (0.58) | ALDH1A1CYP3A4CYP2D6CYP2C19PPID | |
| SCHEMBL7316396 | 0.81 | MME (0.53) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL7416551 | 0.81 | CYP3A4 (0.44) | ALDH1A1CYP3A4CYP2D6CYP2C19PPID | |
| SCHEMBL7384151 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2D6CYP2C19PPIDMMP8 | |
| SCHEMBL10790828 | 0.81 | MME (0.52) | CYP3A4CYP2D6CYP2C19MMP8POLB | |
| SCHEMBL7361284 | 0.80 | LAP3 (0.64) | CYP3A4CYP2D6CYP2C19PPIDMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5262709-A | — | — | None | — | — | JP | disclosed |
| JP-H05262709-A | PROPIONAMIDE DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1993-10-12 | — | — | JP | disclosed |