Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389968 | 0.93 | DRD2 (0.51) | SIGMAR1DRD2CCR3CKS1BSKP1 | |
| SCHEMBL7392116 | 0.89 | SIGMAR1 (0.55) | SIGMAR1DRD2CCR3CKS1BSKP1 | |
| SCHEMBL7385234 | 0.88 | SIGMAR1 (0.52) | SIGMAR1DRD2CKS1BSKP1SKP2 | |
| SCHEMBL7392112 | 0.83 | LTA4H (0.58) | SIGMAR1DRD2 | |
| SCHEMBL7392114 | 0.83 | LTA4H (0.58) | SIGMAR1DRD2 | |
| SCHEMBL3289146 | 0.82 | DRD2 (0.56) | DRD2CKS1BSKP1SKP2ACACB | |
| SCHEMBL14432029 | 0.82 | DRD2 (0.56) | DRD2CKS1BSKP1SKP2ACACB | |
| SCHEMBL5450728 | 0.82 | DRD2 (0.56) | DRD2CKS1BSKP1SKP2ACACB | |
| SCHEMBL19100453 | 0.81 | ACHE (0.50) | SIGMAR1DRD2 | |
| SCHEMBL7973018 | 0.81 | CHRNB2 (0.62) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |