Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400340 | 0.88 | ALOX5 (0.59) | AMY1AALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL7386529 | 0.85 | GUSB (0.57) | AMY1AALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL7386703 | 0.83 | CHEK2 (0.48) | AMY1AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7394125 | 0.81 | AMY1A (0.54) | AMY1AALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL7389940 | 0.81 | ALDH1A1 (0.71) | AMY1AALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL7388752 | 0.81 | KDM4E (0.46) | AMY1AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7395692 | 0.79 | AMY1A (0.62) | AMY1AALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL7392370 | 0.79 | AMY1A (0.46) | AMY1AKDM4EALDH1A1 | |
| SCHEMBL7387113 | 0.77 | AMY1A (0.42) | AMY1AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7397419 | 0.77 | KDM4E (0.52) | AMY1AKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | claimed |
| WO-2001066526-A1 | ESTER DERIVATIVES OF DIMETHYLPROPIONIC ACID AND PHARMACETUICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2001-09-13 | — | — | WO | disclosed |
| EP-1132381-A1 | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2001-09-12 | — | — | EP | disclosed |