Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393385 | 0.89 | SIGMAR1 (0.48) | SIGMAR1DGAT1THRB | |
| SCHEMBL7387185 | 0.85 | TSHR (0.50) | SIGMAR1 | |
| SCHEMBL7387950 | 0.85 | THRB (0.45) | SIGMAR1ITGB3ITGA2BTHRBP2RX3 | |
| SCHEMBL7388767 | 0.85 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BDGAT1THRB | |
| SCHEMBL5530617 | 0.84 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BDGAT1THRB | |
| SCHEMBL7390909 | 0.84 | SMYD3 (0.46) | SIGMAR1ITGB3ITGA2BTHRBP2RX3 | |
| SCHEMBL7392530 | 0.83 | THRB (0.43) | SIGMAR1ITGB3ITGA2BTHRBP2RX3 | |
| SCHEMBL7384950 | 0.82 | FABP6 (0.46) | SIGMAR1ITGB3ITGA2BDGAT1 | |
| SCHEMBL5530623 | 0.82 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BDGAT1THRB | |
| SCHEMBL7473955 | 0.81 | MGLL (0.53) | SIGMAR1ITGB3ITGA2BDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056743-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999031092-A1 | BENZAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1999-06-24 | — | — | WO | disclosed |