Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530617 | 0.88 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BTHRBDGAT1 | |
| SCHEMBL5533939 | 0.85 | THRB (0.44) | SIGMAR1ITGB3ITGA2BTHRB | |
| SCHEMBL7393385 | 0.85 | SIGMAR1 (0.48) | SIGMAR1THRBDGAT1 | |
| SCHEMBL7386854 | 0.84 | DGAT1 (0.42) | SIGMAR1ITGB3ITGA2BDGAT1 | |
| SCHEMBL5535948 | 0.84 | CCR2 (0.40) | SIGMAR1ITGB3ITGA2BTHRBDGAT1 | |
| SCHEMBL7387185 | 0.84 | TSHR (0.50) | SIGMAR1 | |
| SCHEMBL7473955 | 0.83 | MGLL (0.53) | SIGMAR1ITGB3ITGA2BDGAT1 | |
| SCHEMBL7387950 | 0.83 | THRB (0.45) | SIGMAR1ITGB3ITGA2BTHRB | |
| SCHEMBL7388767 | 0.83 | SIGMAR1 (0.45) | SIGMAR1ITGB3ITGA2BTHRBDGAT1 | |
| SCHEMBL7386012 | 0.83 | LMNA (0.44) | SIGMAR1ITGB3ITGA2BDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416931-B1 | INHIBITORS OF POLYQ-AGGREGATION | MAX PLANCK GESELLSCHAFT (DE) | 2007-06-13 | — | — | EP | claimed |