SCHEMBL73908

SCHEMBL73908

COc1ccc2sc(N)nc2c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.75
CYP1A2 P05177 2/20 0.75
CYP2C19 P33261 1/20 0.75
FTO Q9C0B1 1/20 0.57
ILK Q13418 1/20 0.55
BACE1 P56817 1/20 0.54
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
DYRK1A Q13627 1/20 0.54
TP53 P04637 4/20 0.51
ALDH1A1 P00352 2/20 0.51
TSHR P16473 2/20 0.51
HSD17B10 Q99714 2/20 0.51
DRD2 P14416 1/20 0.50
KCNH2 Q12809 1/20 0.50
PIK3CD O00329 1/20 0.50
PIK3CA P42336 1/20 0.50
PIK3CB P42338 1/20 0.50
PIK3CG P48736 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29751964 1.00 CYP3A4 (0.75) CYP3A4CYP1A2CYP2C19FTOILK
Ammonia Solution, Strong SCHEMBL17673950 0.98 CYP3A4 (0.73) CYP3A4CYP1A2CYP2C19FTOILK
SCHEMBL22358 0.86 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19FTONPC1
SCHEMBL29683488 0.86 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19FTONPC1
Hydrochloric Acid SCHEMBL11423357 0.84 CYP3A4 (0.97) CYP3A4CYP1A2CYP2C19FTONPC1
Hydrochloric Acid SCHEMBL11151690 0.84 CYP3A4 (0.97) CYP3A4CYP1A2CYP2C19FTONPC1
Ammonia Solution, Strong SCHEMBL7998249 0.84 CYP3A4 (0.97) CYP3A4CYP1A2CYP2C19FTONPC1
SCHEMBL16992950 0.82 CYP3A4 (0.51) CYP3A4CYP1A2CYP2C19FTONPC1
SCHEMBL31257148 0.81 CYP3A4 (0.77) CYP3A4CYP1A2CYP2C19FTONPC1
SCHEMBL482497 0.81 CYP3A4 (0.77) CYP3A4CYP1A2CYP2C19FTONPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0282971-B1 Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents WARNER LAMBERT CO (US) 1994-12-28 EP claimed
US-4826860-A STROKES WARNER-LAMBERT COMPANY (US) 1989-05-02 US claimed
EP-0282971-A2 Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents WARNER-LAMBERT COMPANY (US) 1988-09-21 EP claimed
EP-0072621-B1 ALKYLENEOXY COMPOUNDS, THEIR PREPARATION AND THEIR USE AS FUGITIVE TINTS MILLIKEN RESEARCH CORPORATION (US) 1985-04-24 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-4722321-A1 GREASE COMPOSITION KYODO YUSHI CO., LTD. (JP) 2026-04-08 EP disclosed
US-12570622-B2 Therapeutic compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-03-10 US disclosed
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INST NAT SANTE RECH MED (FR) 2025-12-18 US disclosed
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
CN-120136812-A Compound for targeted degradation of transcription factor KLF5 and application thereof 昆明医科大学 2025-06-13 CN disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-20250129063-A1 BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS GENENTECH, INC. (US) 2025-04-24 US disclosed
EP-0017009-A2 Dyes and tints based on optionally substituted 2-amino-5-iminopyrrolenines BAYER AG (DE) 1980-10-15 EP disclosed
EP-0017012-A2 Dyes and process for the generation of tints based on optionally substituted 2-amino-5-iminopyrrolenines BAYER AG (DE) 1980-10-15 EP disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4223031-A ANTIALLERGENS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, HYPERSENSITIVITY MEAD JOHNSON & COMPANY (US) 1980-09-16 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
US-4136033-A DIAZO COUPLERS SANDOZ LTD. (CH) 1979-01-23 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-4000135-A IRON TETRAAZANNULENES AS CATALYSTS BASF AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CYP3A4 4633/4885CYP1A2 4806/4885CYP2C19 4830/4885
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS BBOX1, NDUFB6, NDUFB5 CYP3A4 343/4885CYP1A2 57/4885CYP2C19 551/4885
US-12570622-B2 Therapeutic compounds CYP11B1, CYP11B2, NDUFAB1 CYP3A4 477/4885CYP1A2 554/4885CYP2C19 654/4885
US-20250129063-A1 BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS VHL, BRCA1, GLS CYP3A4 4422/4885CYP1A2 4657/4885CYP2C19 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.