Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396129 | 0.82 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL6930563 | 0.81 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL5962892 | 0.81 | KMT2A (0.49) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL3179779 | 0.81 | KMT2A (0.53) | SMN1; SMN2ALDH1A1HTTHPGDKMT2A | |
| SCHEMBL10448699 | 0.81 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL10725427 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL1186097 | 0.76 | LMNA (0.58) | ALDH1A1HTTHPGDKMT2AMEN1 | |
| SCHEMBL14192707 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HTTHPGDKMT2A | |
| SCHEMBL8533644 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HTTHPGDPOLB | |
| SCHEMBL10730796 | 0.75 | MAPT (0.56) | SMN1; SMN2ALDH1A1HTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139257-A1 | PLIN1 RNAi INTERFERENCE AGENTS | ELI LILLY AND CO (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260083854-A1 | CONJUGATES COMPRISING BIS-MSPT LINKER | LILLY CO ELI (US) | 2026-03-26 | — | — | US | disclosed |
| US-20250381284-A1 | PRNP RNAi AGENTS | LILLY CO ELI (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250249118-A1 | SARM1 RNAi AGENTS | ELI LILLY AND COMPANY | 2025-08-07 | — | — | US | disclosed |
| US-20170360740-A1 | HISTONE DEACETYLASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9724321-B2 | Histone deacetylase inhibitors | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160143874-A1 | HISTONE DEACETYLASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. | 2016-05-26 | — | — | US | disclosed |
| US-9199923-B2 | Histone deacetylase inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-01 | — | — | US | disclosed |
| US-20150038581-A1 | HISTONE DEACETYLASE INHIBITORS | Harvard University & Medical School | 2015-02-05 | — | — | US | disclosed |
| WO-2014144878-A2 | NOVEL THIOL & AMINO MODIFYING REAGENTS FOR PROTEIN CHEMISTRY AND METHODS OF USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20100056588-A1 | HISTONE DEACETYLASE INHIBITORS | DANA-FARBER CANCER INSTITUTE, INC. | 2010-03-04 | — | — | US | disclosed |
| US-20090209590-A1 | Histone Deacetylase and Tubulin Deacetylase Inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-08-20 | — | — | US | disclosed |
| US-20080269245-A1 | Dioxanes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2008-10-30 | — | — | US | disclosed |
| US-7244853-B2 | Dioxanes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-07-17 | — | — | US | disclosed |
| US-20040072849-A1 | Dioxanes and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-15 | — | — | US | disclosed |
| US-5843966-A | Piperidine derivatives | GLAXO GROUP LIMITED (GB) | 1998-12-01 | — | — | US | disclosed |
| EP-0720609-B1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| US-5703240-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS; GASTROINTESTINAL DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| EP-0720609-A1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008549-A1 | 3-(5-TETRAZOLYL-BENZYL)AMINO-PIPERIDINE DERIVATIVES AND ANTAGONISTS OF TACHYKININS | GLAXO GROUP LIMITED (GB) | 1995-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143874-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | SMN1; SMN2 2306/4885ALDH1A1 955/4885HTT 1048/4885 |
| US-20090209590-A1 | Histone Deacetylase and Tubulin Deacetylase Inhibitors | HDAC6, HDAC1, HDAC5 | SMN1; SMN2 3990/4885ALDH1A1 320/4885HTT 78/4885 |
| US-20260083854-A1 | CONJUGATES COMPRISING BIS-MSPT LINKER | TFRC, TNFSF11, FTH1 | SMN1; SMN2 812/4885ALDH1A1 4403/4885HTT 391/4885 |
| US-20170360740-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | SMN1; SMN2 2955/4885ALDH1A1 764/4885HTT 1108/4885 |
| US-20040072849-A1 | Dioxanes and uses thereof | UTS2R, HDAC5, AMDHD2 | SMN1; SMN2 3947/4885ALDH1A1 682/4885HTT 3375/4885 |
| US-20250381284-A1 | PRNP RNAi AGENTS | PRNP, SARNP, PCNP | SMN1; SMN2 370/4885ALDH1A1 3554/4885HTT 99/4885 |
| US-20250249118-A1 | SARM1 RNAi AGENTS | SARNP, SARM1, SMN1; SMN2 | SMN1; SMN2 3/4885ALDH1A1 3895/4885HTT 139/4885 |
| US-20260139257-A1 | PLIN1 RNAi INTERFERENCE AGENTS | PLIN1, PLIN3, PLIN5 | SMN1; SMN2 1331/4885ALDH1A1 3231/4885HTT 2361/4885 |
| US-20150038581-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | SMN1; SMN2 2955/4885ALDH1A1 764/4885HTT 1108/4885 |
| US-20100056588-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC7 | SMN1; SMN2 2955/4885ALDH1A1 764/4885HTT 1108/4885 |
| US-20080269245-A1 | Dioxanes and uses thereof | UTS2R, MAN2B2, AMDHD2 | SMN1; SMN2 3819/4885ALDH1A1 750/4885HTT 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.