Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326376 | 0.92 | HSD11B1 (0.36) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL7430275 | 0.86 | PARP1 (0.49) | PARP1HSD11B1HPGD | |
| SCHEMBL8500114 | 0.76 | HTR4 (0.40) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL1502018 | 0.76 | HTR4 (0.51) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL7436836 | 0.75 | MAOA (0.35) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL7332629 | 0.74 | HTR4 (0.41) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL5316552 | 0.73 | HTR4 (0.47) | HTR4HTR3AHTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL7137041 | 0.73 | HTR3A (0.54) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL7393687 | 0.73 | HTR4 (0.74) | HTR4HTR3AHTR1AADRA2CACHE | |
| SCHEMBL5042504 | 0.72 | PTGES (0.37) | HTR4HTR3AMAPTHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502209-A | SIDE EFFECT REDUCTION, GASTROINTESTINAL | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0691341-A1 | Benzopyrancarboxamide derivatives, salt thereof, process for the preparation of same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |