Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364055 | 0.92 | RAB9A (0.48) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7396948 | 0.88 | ABL1 (0.47) | MEN1KMT2AGSK3BPLK1RAB9A | |
| SCHEMBL7366117 | 0.84 | P4HTM (0.53) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7391711 | 0.81 | MEN1 (0.45) | ALOX12L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL10338395 | 0.80 | KCNH2 (0.43) | MEN1KMT2AGSK3BNPC1RAB9A | |
| SCHEMBL7398132 | 0.80 | VCP (0.40) | ALOX12L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL7396951 | 0.76 | KMT2A (0.62) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9669035 | 0.75 | PRKAB2 (0.35) | MAPT | |
| SCHEMBL7396855 | 0.74 | MEN1 (0.46) | MEN1KMT2APLK1NPC1RAB9A | |
| SCHEMBL10830069 | 0.73 | ALDH1A1 (0.36) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096517-A2 | Aryl pyrazinones | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |