Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401262 | 0.83 | ITGB3 (0.42) | ALDH1A1GAALMNAITGB3ITGAV | |
| SCHEMBL7917615 | 0.82 | ITGB3 (0.41) | ALDH1A1GAALMNAITGB3ITGAV | |
| SCHEMBL7078802 | 0.81 | ITGB3 (0.49) | ITGB3ITGAVMAPT | |
| SCHEMBL7398660 | 0.81 | DRD2 (0.39) | ALDH1A1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8525635 | 0.79 | JAK2 (0.46) | ALDH1A1GAALMNAITGB3ITGAV | |
| SCHEMBL14279562 | 0.76 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL7437290 | 0.71 | PNMT (0.42) | ALDH1A1MAPTPNMTADRA2AADRA2B | |
| SCHEMBL9021160 | 0.70 | GAA (0.43) | GAAITGB3ITGAV | |
| SCHEMBL9021166 | 0.70 | GAA (0.43) | GAAITGB3ITGAV | |
| SCHEMBL7514000 | 0.70 | ALDH1A1 (0.51) | ALDH1A1GAALMNAPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6127359-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0593603-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-27 | — | — | EP | disclosed |
| WO-1993000095-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-07 | — | — | WO | disclosed |