Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.47 |
| ▸ | MMP3 | P08254 | 10/20 | 0.47 |
| ▸ | MMP1 | P03956 | 5/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP20 | O60882 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP10 | P09238 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MMP15 | P51511 | 1/20 | 0.44 |
| ▸ | MMP16 | P51512 | 1/20 | 0.44 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.44 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7765095 | 0.79 | MMP2 (0.52) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL8887821 | 0.75 | MMP1 (0.76) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL8899210 | 0.75 | MMP1 (0.76) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL8026514 | 0.75 | MMP1 (0.76) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL7371075 | 0.73 | MTOR (0.41) | — | |
| SCHEMBL20182067 | 0.73 | MEN1 (0.51) | — | |
| SCHEMBL8026827 | 0.72 | ADAM17 (0.77) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL7411892 | 0.72 | MMP2 (0.44) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL9287415 | 0.70 | MMP2 (0.70) | MMP2MMP3MMP1ADAM17TNF | |
| SCHEMBL6951443 | 0.69 | ADAM17 (0.61) | MMP2MMP3MMP1ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740652-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1998-05-06 | — | — | EP | claimed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | claimed |
| US-5929093-A | PYRIDINIUM ALDOXIME SALTS; ANTIDOTES FOR ORGANOPHOSPHATE POISONING IN MAMMALS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |