Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400099 | 0.84 | REN (0.49) | RENLMNA | |
| SCHEMBL7408564 | 0.82 | CTRB1 (0.44) | CTRB1RENTSHRL3MBTL1KDM4E | |
| SCHEMBL7404038 | 0.82 | REN (0.53) | REN | |
| SCHEMBL7405000 | 0.81 | REN (0.45) | REN | |
| SCHEMBL8605875 | 0.80 | PSEN1 (0.56) | REN | |
| SCHEMBL7394330 | 0.79 | CTSD (0.49) | REN | |
| SCHEMBL7402232 | 0.79 | CTSD (0.46) | REN | |
| SCHEMBL8664644 | 0.79 | CTSD (0.48) | REN | |
| SCHEMBL7396675 | 0.78 | CTSD (0.47) | REN | |
| SCHEMBL7403620 | 0.78 | CTSD (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750648-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1998-05-12 | — | — | US | claimed |
| WO-1995006061-A1 | RETROVIRAL PROTEASE INHIBITORS AND COMBINATIONS THEREOF | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | claimed |