Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403288 | 0.78 | LMNA (0.49) | LMNAALDH1A1TP53SMN1; SMN2KDM4E | |
| SCHEMBL7402340 | 0.77 | LMNA (0.70) | LMNAALDH1A1GAATP53SMN1; SMN2 | |
| SCHEMBL27455057 | 0.77 | LMNA (0.47) | LMNAALDH1A1TP53SMN1; SMN2KDM4E | |
| SCHEMBL2222532 | 0.71 | ENPP2 (0.41) | LMNAALDH1A1SMN1; SMN2KDM4EADORA2A | |
| SCHEMBL571266 | 0.66 | ALDH1A1 (0.46) | LMNAALDH1A1GAATP53SMN1; SMN2 | |
| SCHEMBL3435968 | 0.66 | PGAM1 (0.39) | LMNAALDH1A1KDM4EHIF1AMAPT | |
| SCHEMBL15713879 | 0.66 | MEN1 (0.49) | LMNAALDH1A1GAATP53SMN1; SMN2 | |
| SCHEMBL4818821 | 0.65 | LMNA (0.56) | LMNAALDH1A1TP53SMN1; SMN2HIF1A | |
| SCHEMBL4749775 | 0.64 | AKT2 (0.66) | TP53RPS6KA3CHEK1RETPDGFRB | |
| SCHEMBL16260565 | 0.64 | KDM4E (0.57) | LMNAALDH1A1GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658106-A1 | ORAL CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2020-06-03 | — | — | EP | disclosed |
| WO-2019045781-A1 | ORAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-3365028-A1 | DETECTION AND TREATMENT OF CARIES AND MICROCAVITIES WITH NANOPARTICLES | The Regents of The University of Michigan (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070578-A1 | DETECTION AND TREATMENT OF CARIES AND MICROCAVITIES WITH NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-04-27 | — | — | WO | disclosed |
| CN-103596545-A | Stabilization of zinc oxide films in oral compositions | COLGATE PALMOLIVE CO | 2014-02-19 | — | — | CN | disclosed |
| CN-103096979-A | Oral care formulations for malodor control | COLGATE PALMOLIVE CO | 2013-05-08 | — | — | CN | disclosed |
| EP-2249770-A2 | DUAL COMPONENT ORAL CARE PRODUCT | Colgate-Palmolive Company (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100268-A2 | DUAL COMPONENT ORAL CARE PRODUCT | COLGATE-PALMOLIVE COMPANY (US) | 2009-08-13 | — | — | WO | disclosed |
| CN-1191052-C | Dual component dentinal desensitizing dentifrice | COLGATE PALMOLIVE CO (US) | 2005-03-02 | — | — | CN | disclosed |
| CN-1343112-A | Dual component dentinal desensitizing dentifrice | COLGATE PALMOLIVE CO (US) | 2002-04-03 | — | — | CN | disclosed |