Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2222532 | 0.74 | ENPP2 (0.41) | ALPLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27455057 | 0.73 | LMNA (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL6338048 | 0.69 | TSHR (0.45) | PGAM1ALPLNFKB1L3MBTL1KDM4A | |
| SCHEMBL458284 | 0.68 | SMN1; SMN2 (0.48) | PGAM1ALPLNFKB1L3MBTL1KDM4A | |
| SCHEMBL460174 | 0.66 | STAT3 (0.51) | PGAM1ALPLNFKB1L3MBTL1KDM4A | |
| SCHEMBL28837581 | 0.66 | SMN1; SMN2 (0.46) | PGAM1ALPLNFKB1L3MBTL1KDM4A | |
| SCHEMBL232659 | 0.65 | CASP1 (0.47) | PGAM1TSHRHSD17B10ALDH1A1AKR1B1 | |
| SCHEMBL29743050 | 0.65 | CASP1 (0.47) | PGAM1TSHRHSD17B10ALDH1A1AKR1B1 | |
| SCHEMBL776521 | 0.64 | PGAM1 (0.46) | PGAM1ALPLNFKB1L3MBTL1KDM4A | |
| SCHEMBL20837285 | 0.64 | LMNA (0.47) | NFKB1L3MBTL1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658106-A1 | ORAL CARE COMPOSITIONS | Colgate-Palmolive Company (US) | 2020-06-03 | — | — | EP | disclosed |
| WO-2019045781-A1 | ORAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-3365028-A1 | DETECTION AND TREATMENT OF CARIES AND MICROCAVITIES WITH NANOPARTICLES | The Regents of The University of Michigan (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070578-A1 | DETECTION AND TREATMENT OF CARIES AND MICROCAVITIES WITH NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-04-27 | — | — | WO | disclosed |
| EP-2249770-A2 | DUAL COMPONENT ORAL CARE PRODUCT | Colgate-Palmolive Company (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100268-A2 | DUAL COMPONENT ORAL CARE PRODUCT | COLGATE-PALMOLIVE COMPANY (US) | 2009-08-13 | — | — | WO | disclosed |