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Ethylene Glycol

Ethylene Glycol

SCHEMBL7403700

CC(C)(C)OC(=O)N1CCC(CCc2cc3sc(C=O)cc3s2)CC1.CCOC(C)OCC.OCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLS O94925 2/20 0.38
▸ FAAH O00519 1/20 0.37
▸ GPR119 Q8TDV5 12/20 0.36
▸ DPP4 P27487 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ MMP13 P45452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7399144 0.89 GLS (0.45) GLSFAAHGPR119KDM4EPKM
Ethylene Glycol SCHEMBL7399885 0.88 GLS (0.37) GLSFAAHGPR119DPP4KDM4E
SCHEMBL7445509 0.76 GLS (0.43) GLSFAAHGPR119KDM4EPKM
SCHEMBL7401060 0.76 KDM4E (0.45) GLSFAAHGPR119KDM4EPKM
SCHEMBL7403703 0.73 FAAH (0.42) GLSFAAHGPR119DPP4KDM4E
SCHEMBL7403382 0.71 KDM4E (0.42) GLSFAAHGPR119KDM4EPKM
SCHEMBL7370728 0.69 KDM4E (0.47) FAAHGPR119KDM4EPKMMMP13
SCHEMBL7086084 0.67 RECQL (0.48) GLSFAAHGPR119KDM4EPKM
SCHEMBL7399174 0.66 ITGB3 (0.46) GLSFAAHGPR119KDM4EPKM
SCHEMBL310405 0.66 HPGD (0.54) FAAHGPR119KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714295-B1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 2000-12-20 — — EP disclosed
US-5397791-A Anticoagulants MERCK & CO., INC. (US) 1995-03-14 — — US disclosed
WO-1995004531-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-02-16 — — WO disclosed