Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399888 | 0.86 | FAAH (0.41) | FAAHGPR119SCN9AKDM4EMAPT | |
| SCHEMBL7401060 | 0.82 | KDM4E (0.45) | FAAHGPR119KDM4EMAPTTHRB | |
| SCHEMBL7399144 | 0.82 | GLS (0.45) | FAAHGPR119KDM4EMAPTTHRB | |
| SCHEMBL7370728 | 0.75 | KDM4E (0.47) | FAAHGPR119KDM4EPKM | |
| Ethylene Glycol SCHEMBL7403700 | 0.73 | GLS (0.38) | FAAHGPR119KDM4EGLSPKM | |
| SCHEMBL7445509 | 0.72 | GLS (0.43) | FAAHGPR119KDM4EMAPTTHRB | |
| SCHEMBL7399174 | 0.72 | ITGB3 (0.46) | FAAHGPR119KDM4EMAPTTHRB | |
| SCHEMBL9035867 | 0.71 | KDM4E (0.52) | FAAHGPR119KDM4EPKM | |
| SCHEMBL20015308 | 0.70 | DPP4 (0.65) | GPR119SCN9AKDM4EPKMDPP4 | |
| SCHEMBL31622247 | 0.70 | RECQL (0.54) | FAAHGPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714295-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5397791-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1995004531-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-16 | — | — | WO | disclosed |