Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL7399885 | 0.89 | GLS (0.37) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7399174 | 0.85 | ITGB3 (0.46) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7399144 | 0.85 | GLS (0.45) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7399888 | 0.83 | FAAH (0.41) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7403382 | 0.82 | KDM4E (0.42) | GLSFAAHKDM4EPKMGPR119 | |
| Ethylene Glycol SCHEMBL7403700 | 0.76 | GLS (0.38) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7370728 | 0.76 | KDM4E (0.47) | FAAHKDM4EPKMGPR119 | |
| SCHEMBL7401060 | 0.74 | KDM4E (0.45) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL7403703 | 0.72 | FAAH (0.42) | GLSFAAHKDM4EPKMGPR119 | |
| SCHEMBL27393684 | 0.72 | FAAH (0.49) | FAAHKDM4EPKMGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714295-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5646000-A | FLUORESCENT PROBES FOR INDENTIFYING ANTIPLATELET AGENTS | MERCK & CO., INC. (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0714295-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714295-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1996010181-A1 | COMPOUNDS AND METHODS FOR IDENTIFYING ACTIVATED PLATELETS | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |
| US-5397791-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1995004531-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-02-16 | — | — | WO | disclosed |