Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400458 | 0.89 | ALDH1A1 (0.42) | HRH3MAPTALDH1A1KDM4EHTT | |
| SCHEMBL7404796 | 0.79 | MAPT (0.58) | MAPTALDH1A1KDM4EHTTTSHR | |
| SCHEMBL7327928 | 0.76 | HRH3 (0.59) | HRH3ALDH1A1ITGB3ITGA2BKDM4E | |
| SCHEMBL8605546 | 0.74 | MEN1 (0.48) | HRH3MAPTALDH1A1ITGB3ITGA2B | |
| SCHEMBL7397082 | 0.74 | LOXL2 (0.45) | HRH3ALDH1A1ITGB3ITGA2BKDM4E | |
| SCHEMBL8654154 | 0.73 | SLC27A1 (0.37) | MAPTALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL7403964 | 0.72 | MAPT (0.54) | HRH3MAPTALDH1A1ITGB3ITGA2B | |
| SCHEMBL7403264 | 0.71 | MAPT (0.80) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7400283 | 0.69 | MAPT (0.58) | MAPTALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7399638 | 0.67 | HRH3 (0.58) | HRH3MAPTALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |