Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC27A1 | Q6PCB7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654157 | 0.79 | TSHR (0.40) | SLC27A1ALDH1A1GAATSHRMAPT | |
| SCHEMBL8696288 | 0.74 | HSD17B10 (0.36) | ALDH1A1TSHRHSD17B10ABCB1KDM4E | |
| SCHEMBL7404196 | 0.73 | HRH3 (0.42) | ALDH1A1TSHRMAPTABCB1KDM4E | |
| SCHEMBL8654165 | 0.69 | PDGFRB (0.33) | ALDH1A1TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL8630368 | 0.63 | ITGB3 (0.44) | ALDH1A1TSHRMAPTHSD17B10LMNA | |
| SCHEMBL7406379 | 0.63 | NCF1 (0.49) | — | |
| SCHEMBL8604342 | 0.60 | HRH3 (0.53) | ALDH1A1TSHRMAPTKDM4ELMNA | |
| SCHEMBL2560281 | 0.59 | LDHA (0.65) | GAA | |
| SCHEMBL20592934 | 0.59 | LDHA (0.47) | ALDH1A1GAATSHR | |
| SCHEMBL26134046 | 0.59 | LDHA (0.52) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |