Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409272 | 0.81 | MEN1 (0.46) | MEN1KMT2ARAB9A | |
| SCHEMBL7409091 | 0.74 | MEN1 (0.46) | MEN1KMT2AGRIN2BNPC1RAB9A | |
| SCHEMBL7407388 | 0.71 | ELANE (0.43) | GRIN2BELANE | |
| SCHEMBL7413306 | 0.70 | — | — | |
| SCHEMBL7411308 | 0.70 | NPC1 (0.41) | NPC1 | |
| SCHEMBL7875386 | 0.67 | NPSR1 (0.53) | MEN1KMT2AGRIN2BNPC1RAB9A | |
| SCHEMBL6230666 | 0.66 | ALDH1A1 (0.52) | MEN1KMT2AGRIN2B | |
| SCHEMBL7401667 | 0.66 | ELANE (0.58) | ELANE | |
| SCHEMBL7511361 | 0.66 | ELANE (0.60) | ELANE | |
| SCHEMBL7511367 | 0.66 | ELANE (0.60) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973775-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043975-A1 | PYROLOPYRROLONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |