Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417232 | 0.92 | BRD4 (0.41) | HTR1FMMP1MMP2MMP9MMP12 | |
| SCHEMBL7412952 | 0.88 | RAB9A (0.45) | LMNAGFERALOX15MAPK1CASP1 | |
| SCHEMBL7409574 | 0.85 | ALDH1A1 (0.45) | HTR1FLMNAGFERALOX15MAPK1 | |
| Hydrochloric Acid SCHEMBL7407346 | 0.84 | ALDH1A1 (0.44) | HTR1FKDM4ELMNAGFERALOX15 | |
| SCHEMBL7407705 | 0.84 | CHRM2 (0.39) | HTR1FGFERALOX15MAPK1CASP1 | |
| SCHEMBL7409117 | 0.79 | GFER (0.59) | HTR1FKDM4EGFERALOX15MAPK1 | |
| SCHEMBL7409296 | 0.78 | HTR6 (0.41) | HTR1FPTGDR2HTR6TP53 | |
| Water SCHEMBL7414567 | 0.78 | GFER (0.57) | HTR1FKDM4EGFERALOX15MAPK1 | |
| SCHEMBL7410680 | 0.78 | ALOX15 (0.60) | HTR1FGFERALOX15MAPK1CASP1 | |
| SCHEMBL7413250 | 0.78 | GFER (0.45) | HTR1FGFERALOX15MAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |