Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417986 | 0.83 | PKM (0.51) | PKMALDH1A1LMNAPOLBTP53 | |
| SCHEMBL10461474 | 0.82 | PKM (0.63) | PKMALDH1A1GAAHTTPOLB | |
| SCHEMBL7411614 | 0.81 | GAA (0.53) | PKMALDH1A1GAAPOLBHPGD | |
| SCHEMBL7418439 | 0.76 | HSD11B1 (0.55) | HTTLMNAKMT2A | |
| SCHEMBL7415265 | 0.75 | GLA (0.54) | ALDH1A1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7415163 | 0.75 | SLC6A3 (0.55) | ALDH1A1HTT | |
| SCHEMBL7416721 | 0.72 | HTR2A (0.49) | — | |
| SCHEMBL30939415 | 0.72 | CCR6 (0.70) | PKMALDH1A1HTTLMNAPOLB | |
| SCHEMBL7409088 | 0.72 | DPP4 (0.47) | ALDH1A1LMNA | |
| SCHEMBL3964613 | 0.71 | MEN1 (0.79) | ALDH1A1GAAHTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |