Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417986 | 0.87 | PKM (0.51) | PKMPOLBALDH1A1RXFP1 | |
| SCHEMBL7410409 | 0.81 | PKM (0.55) | GAAPKMPOLBALDH1A1KMT2A | |
| SCHEMBL7416706 | 0.78 | KMT2A (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL10461474 | 0.78 | PKM (0.63) | GAAPKMPOLBALDH1A1KMT2A | |
| SCHEMBL7407232 | 0.77 | FAAH (0.51) | KMT2AMEN1 | |
| SCHEMBL7409332 | 0.77 | SLC6A3 (0.41) | — | |
| SCHEMBL22868442 | 0.74 | GAA (0.85) | GAAPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL14470115 | 0.71 | MEN1 (0.75) | GAAPKMPOLBALDH1A1KMT2A | |
| SCHEMBL7411767 | 0.71 | HTR2A (0.59) | — | |
| SCHEMBL7411174 | 0.68 | ALDH1A1 (0.61) | GAAPKMPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |