Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | RB1 | P06400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409813 | 0.93 | MTNR1A (0.47) | MTNR1AMTNR1BRB1 | |
| SCHEMBL7410643 | 0.90 | DRD2 (0.44) | DRD2DRD3RB1 | |
| SCHEMBL7408004 | 0.77 | APOL1 (0.43) | MTNR1AMTNR1BRB1 | |
| SCHEMBL11344966 | 0.76 | APOL1 (0.38) | DRD2 | |
| SCHEMBL7413287 | 0.74 | APOL1 (0.37) | DRD2DRD3 | |
| SCHEMBL7406266 | 0.74 | NR2E1 (0.55) | MTNR1AMTNR1BRB1 | |
| SCHEMBL7407184 | 0.74 | TMEM97 (0.41) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7406790 | 0.73 | TMEM97 (0.40) | DRD2DRD3 | |
| SCHEMBL7660703 | 0.72 | HTR1F (0.49) | DRD2 | |
| SCHEMBL7658867 | 0.72 | HTR1F (0.51) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |