Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7233487 | 0.77 | EGFR (0.48) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL7411401 | 0.74 | RAB9A (0.47) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL2147079 | 0.69 | ALDH1A1 (0.66) | MLKLRAB9AKDM4ETP53SMN1; SMN2 | |
| SCHEMBL7086732 | 0.67 | MAPT (0.46) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL13325930 | 0.66 | AKT2 (0.69) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL12056713 | 0.66 | ALOX5 (0.54) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL7241464 | 0.65 | CYP11B1 (0.42) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL13325933 | 0.64 | SMN1; SMN2 (0.60) | RAB9AKDM4EMAPTTP53SMN1; SMN2 | |
| SCHEMBL8594223 | 0.64 | MLKL (0.50) | MLKLRAB9AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL16756243 | 0.63 | ALPL (0.58) | MLKLRAB9AKDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002002557-A2 | 2-PHENYLIMIDAZO[1,2-A]PYRIDINE DERIVATIVES: A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |