SCHEMBL7412484

SCHEMBL7412484

O=C(NCC(O)Cc1ccccc1)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 1/20 0.46
MMP2 P08253 2/20 0.45
TRPA1 O75762 2/20 0.44
CES1 P23141 1/20 0.43
HCRTR2 O43614 1/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
CYP1A2 P05177 1/20 0.42
PPARG P37231 2/20 0.41
PPARA Q07869 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
BCHE P06276 2/20 0.41
CTRB1 P17538 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10279310 0.83 MTOR (0.46) BCHE
SCHEMBL2636331 0.81 TRPA1 (0.50) MMP2TRPA1MTNR1AMTNR1BTSHR
SCHEMBL1565854 0.76 ALDH1A1 (0.52) MTNR1AMTNR1B
SCHEMBL4632826 0.76 TACR1 (0.56) MTNR1AMTNR1B
SCHEMBL30471275 0.75 RIPK1 (0.61) CES1TSHRCYP1A2
SCHEMBL4765237 0.75 RIPK1 (0.61) CES1TSHRCYP1A2
SCHEMBL27210135 0.75 THRB (0.48) MMP2TRPA1CYP1A2
Trifluoroacetic Acid SCHEMBL27529792 0.75 CPA3 (0.53) CPA1TRPA1CES1CYP1A2PPARG
SCHEMBL4849153 0.74 SLC15A1 (0.53) CPA1MMP2
SCHEMBL10188447 0.74 ATM (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287605-A1 AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1988-10-26 EP disclosed
WO-1988002363-A1 AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) 1988-04-07 WO disclosed