Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420016 | 0.84 | ALDH1A1 (0.42) | ALDH1A1PKMGAAMAPTMEN1 | |
| SCHEMBL7409714 | 0.78 | ALDH1A1 (0.39) | ALDH1A1PKMGAAMAPTMEN1 | |
| SCHEMBL7413734 | 0.73 | HSD11B1 (0.36) | ALDH1A1F2F10PRSS1PRSS2 | |
| SCHEMBL7420806 | 0.73 | ALDH1A1 (0.38) | ALDH1A1PKMF2F10GAA | |
| SCHEMBL7097054 | 0.73 | ALDH1A1 (0.38) | ALDH1A1PKMF2F10GAA | |
| SCHEMBL7420037 | 0.72 | ALDH1A1 (0.37) | ALDH1A1PKMGAAMAPTMEN1 | |
| SCHEMBL5089199 | 0.72 | FASN (0.41) | HSD11B1FASN | |
| SCHEMBL7415075 | 0.71 | F2 (0.74) | ALDH1A1F2F10PRSS1PRSS2 | |
| SCHEMBL7414201 | 0.70 | ALDH1A1 (0.35) | ALDH1A1PKMGAAMAPTMEN1 | |
| SCHEMBL5099562 | 0.70 | NPC1 (0.43) | ALDH1A1GAAMAPTKMT2AFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |