Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 4/20 | 0.37 |
| ▸ | FPR2 | P25090 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420806 | 0.82 | ALDH1A1 (0.38) | ALDH1A1PKMFPR1FPR2MEN1 | |
| SCHEMBL7411883 | 0.75 | AAK1 (0.41) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7412573 | 0.72 | ALDH1A1 (0.42) | ALDH1A1PKMMEN1KMT2AGAA | |
| SCHEMBL7421439 | 0.72 | HCAR3 (0.40) | ALDH1A1PKMCTSKCTSSMEN1 | |
| SCHEMBL5151249 | 0.68 | FPR2 (0.59) | FPR1FPR2CTSKCTSSKMT2A | |
| SCHEMBL6767381 | 0.68 | FPR2 (0.59) | FPR1FPR2CTSKCTSSKMT2A | |
| SCHEMBL5155529 | 0.68 | FPR2 (0.59) | FPR1FPR2CTSKCTSSKMT2A | |
| SCHEMBL21468963 | 0.68 | CTSK (0.43) | CTSKCTSSMEN1KMT2ACTSL | |
| SCHEMBL16379880 | 0.68 | CTSK (0.43) | CTSKCTSSMEN1KMT2ACTSL | |
| SCHEMBL21469088 | 0.68 | MTTP (0.37) | CTSKCTSSMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-B1 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6248770-B1 | CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-06-19 | — | — | US | disclosed |