Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558171 | 1.00 | RIPK1 (0.46) | RIPK1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7423810 | 0.89 | LTA4H (0.57) | LAP3 | |
| SCHEMBL7807967 | 0.84 | LAP3 (0.43) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL7348250 | 0.83 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7412834 | 0.82 | SLC15A1 (0.50) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7412831 | 0.82 | SLC15A1 (0.50) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL6558239 | 0.81 | CYP1A2 (0.47) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Hydrochloric Acid SCHEMBL6558386 | 0.79 | HRH4 (0.45) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Trifluoroacetic Acid SCHEMBL17106970 | 0.78 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPMMP8 | |
| Trifluoroacetic Acid SCHEMBL17106974 | 0.78 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |