Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143794 | 0.94 | HTR6 (0.46) | BACE1HTR6TSHRUSP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7411758 | 0.82 | ABL1 (0.45) | HTR6POLB | |
| Trifluoroacetic Acid SCHEMBL7522281 | 0.80 | ALDH1A1 (0.49) | TSHRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7379635 | 0.80 | TRPV1 (0.45) | — | |
| Trifluoroacetic Acid SCHEMBL7376343 | 0.79 | ME3 (0.48) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL8141371 | 0.76 | POLB (0.46) | POLB | |
| SCHEMBL8142733 | 0.76 | TRPV1 (0.47) | — | |
| SCHEMBL8150390 | 0.73 | HPGD (0.54) | TSHRALDH1A1 | |
| SCHEMBL7375780 | 0.71 | BACE1 (0.46) | BACE1POLB | |
| SCHEMBL7371765 | 0.71 | ME3 (0.54) | POLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |