Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150390 | 0.94 | HPGD (0.54) | ALDH1A1HPGDTSHRNPY2RHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL7379635 | 0.90 | TRPV1 (0.45) | NPY2RKMT2AMEN1MAPTITGB3 | |
| SCHEMBL8142733 | 0.87 | TRPV1 (0.47) | NPY2RHSP90AA1HSP90AB1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL7376343 | 0.85 | ME3 (0.48) | ALDH1A1MALT1KMT2AMEN1MAPT | |
| Trifluoroacetic Acid SCHEMBL7413403 | 0.80 | BACE1 (0.45) | ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL7411758 | 0.79 | ABL1 (0.45) | MAPT | |
| SCHEMBL7371765 | 0.78 | ME3 (0.54) | ALDH1A1MALT1KMT2AMEN1MAPT | |
| SCHEMBL24630443 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRNPY2RMALT1 | |
| SCHEMBL8143794 | 0.73 | HTR6 (0.46) | ALDH1A1HPGDTSHRKMT2AMEN1 | |
| SCHEMBL8141371 | 0.73 | POLB (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |