SCHEMBL741474

SCHEMBL741474

O=P(O)(O)Oc1ccc(/C=C/c2cc(OP(=O)(O)O)cc(OP(=O)(O)O)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 4/20 0.59
INPP5A Q14642 3/20 0.59
TTR P02766 3/20 0.50
KDM4E B2RXH2 3/20 0.50
SRC P12931 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
LMNA P02545 2/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ESR1 P03372 4/20 0.48
CYP1A1 P04798 3/20 0.48
PTGS2 P35354 3/20 0.48
CYP1B1 Q16678 3/20 0.48
NQO2 P16083 3/20 0.48
ABL1 P00519 2/20 0.48
ABCB1 P08183 2/20 0.48
ALOX5 P09917 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4736118 0.90 CYP1A1 (0.66) TTRKDM4EMEN1MAPTKMT2A
SCHEMBL4734848 0.90 CYP1A1 (0.66) TTRKDM4EMEN1MAPTKMT2A
SCHEMBL12205333 0.88 INPPL1 (0.46) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL30340032 0.87 PTGS1 (0.58) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL2193074 0.84 PTGS2 (0.60) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL30340348 0.84 PTGS2 (0.60) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL6951492 0.83 KDM4E (0.50) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL9019350 0.83 SRC (0.67) INPPL1INPP5ASRCKMT2ACA1
SCHEMBL4166639 0.83 PTGS2 (0.58) INPPL1INPP5ATTRKDM4ESRC
SCHEMBL4261552 0.82 PTGS2 (0.64) INPPL1INPP5AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017835-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE L'OREAL (FR) 2025-01-16 US claimed
CN-118742282-A Cosmetic or dermatological composition comprising a merocyanine and resveratrol and/or resveratrol derivative 莱雅公司 2024-10-01 CN claimed
WO-2023110764-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE L'OREAL (FR) 2023-06-22 WO claimed
US-9782448-B2 Methods and compositions for treating skin ELC MANAGEMENT LLC (US) 2017-10-10 US claimed
EP-3104836-A1 METHOD, COMPOSITIONS, AND KIT FOR MODULATING THE APPEARANCE OF VOLUME ON KERATIN SURFACES ELC Management LLC (US) 2016-12-21 EP claimed
US-20160354303-A1 Method, Compositions, And Kit For Modulating The Appearance Of Volume On Keratin Surfaces ELC MAN LLC (US) 2016-12-08 US claimed
WO-2015123115-A1 METHOD, COMPOSITIONS, AND KIT FOR MODULATING THE APPEARANCE OF VOLUME ON KERATIN SURFACES ELC MANAGEMENT LLC (US) 2015-08-20 WO claimed
US-20140161898-A1 Methods and Compositions for Treating Skin ELC MANAGEMENT, LLC (US) 2014-06-12 US claimed
US-8535738-B2 Methods and compositions for treating skin ELC MANAGEMENT, LLC (US) 2013-09-17 US claimed
US-8465973-B2 Topical compositions containing phosphorylated polyphenols ESTEE LAUDER COORDINATION CENTER N.V. (BE) 2013-06-18 US claimed
EP-2429481-A2 METHOD AND COMPOSITIONS FOR IMPROVING SKIN AND BODY APPEARANCE ELC Management LLC (US) 2012-03-21 EP claimed
US-20110268688-A1 METHOD AND COMPOSITIONS FOR IMPROVING SKIN AND BODY APPEARANCE ELC MANAGEMENT LLC 2011-11-03 US claimed
WO-2010146142-A9 METHODS AND COMPOUNDS FOR REDUCING ALLERGIC REACTIONS TO HAIR DYES HDS LIMITED (GB) 2011-06-16 WO claimed
WO-2009158248-A2 METHOD AND COMPOSITIONS FOR IMPROVING SKIN AND BODY APPEARANCE ELC MANAGEMENT LLC (US) 2009-12-30 WO claimed
US-20090247490-A1 Topical Compositions Containing Phosphorylated Polyphenols DECLERCQ LIEVE 2009-10-01 US claimed
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent ELC MANAGEMENT LLC 2009-02-05 US claimed
US-20250017835-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE L'OREAL (FR) 2025-01-16 US disclosed
EP-4291301-B1 NON-INVASIVE CANCER TREATMENT SCIENTIA BIOTECH S L (ES) 2025-01-15 EP disclosed
WO-2006029484-A1 TOPICAL COMPOSITIONS CONTAINING PHOSPHORYLATED POLYPHENOLS AJINOMOTO OMNICHEM S.A. (BE) 2006-03-23 WO disclosed
WO-2006029483-A1 PHOSPHORYLATED POLYPHENOLS AS COLOUR-STABLE AGENTS AJINOMOTO OMNICHEM S.A. (BE) 2006-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247490-A1 Topical Compositions Containing Phosphorylated Polyphenols PPP5C, CHAMP1, PLK1 INPPL1 146/4885INPP5A 327/4885TTR 1134/4885
US-20250017835-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND RESVERATROL AND/OR A RESVERATROL DERIVATIVE KRT18, ECH1, VIM INPPL1 4217/4885INPP5A 4573/4885TTR 1983/4885
US-20160354303-A1 Method, Compositions, And Kit For Modulating The Appearance Of Volume On Keratin Surfaces KRT18, KIT, KLKB1 INPPL1 3292/4885INPP5A 4492/4885TTR 1506/4885
US-20090035236-A1 Emulsion Cosmetic Compositions Containing Resveratrol Derivatives And An Oil Phase Structuring Agent CUTA, LRAT, RARA INPPL1 1686/4885INPP5A 2663/4885TTR 1922/4885
US-20140161898-A1 Methods and Compositions for Treating Skin LTB4R2, LTB4R, CYSLTR2 INPPL1 1296/4885INPP5A 3408/4885TTR 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.