Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516433 | 0.73 | GAA (0.49) | ALDH1A1MEN1KMT2AKDM4CALOX15 | |
| SCHEMBL20516432 | 0.73 | GAA (0.49) | ALDH1A1MEN1KMT2AKDM4CALOX15 | |
| SCHEMBL16577067 | 0.68 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7543136 | 0.68 | MEN1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5871291 | 0.67 | NPC1 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27733749 | 0.67 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL9485689 | 0.65 | FABP7 (0.42) | ALDH1A1SMN1; SMN2HTR2C | |
| SCHEMBL20516384 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20516387 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL20516416 | 0.64 | CES2 (0.44) | MEN1KMT2ATSHRKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391901-B1 | Thrombin inhibitors | ELI LILLY AND COMPANY | 2002-05-21 | — | — | US | disclosed |
| EP-1027051-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1027051-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |