Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407705 | 0.81 | CHRM2 (0.39) | TP53MAPTHTR1F | |
| SCHEMBL7417232 | 0.81 | BRD4 (0.41) | MAPTHTR1F | |
| SCHEMBL7409574 | 0.80 | ALDH1A1 (0.45) | TP53HTR1F | |
| SCHEMBL7408368 | 0.80 | MAPT (0.41) | HTR6TP53MAPTPTGDR2 | |
| Hydrochloric Acid SCHEMBL7407346 | 0.80 | ALDH1A1 (0.44) | TP53HTR1F | |
| SCHEMBL7417151 | 0.78 | HTR1F (0.47) | HTR6TP53PTGDR2HTR1F | |
| SCHEMBL7402708 | 0.78 | HTR1D (0.45) | HTR6MAPTHTR2AHTR1F | |
| SCHEMBL7412016 | 0.77 | HTR1F (0.40) | HTR6MAPTHTR1F | |
| SCHEMBL7412952 | 0.76 | RAB9A (0.45) | MAPT | |
| SCHEMBL7411494 | 0.76 | HTR1F (0.41) | HTR6MAPTHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |