Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7418650 | 0.98 | GNAO1 (0.41) | NAAAITGB3ITGA2BGNAI3GNAO1 | |
| SCHEMBL6050125 | 0.90 | NAAA (0.46) | NAAAITGB3ITGA2BGNAI3GNAO1 | |
| SCHEMBL28085500 | 0.87 | NAAA (0.47) | NAAA | |
| SCHEMBL27986982 | 0.86 | GNAO1 (0.43) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL25022401 | 0.83 | SMN1; SMN2 (0.46) | NAAA | |
| SCHEMBL3624797 | 0.81 | SLC6A1 (0.41) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL3923983 | 0.81 | LMNA (0.41) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL16470982 | 0.81 | SMN1; SMN2 (0.49) | NAAA | |
| SCHEMBL27627251 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL9344097 | 0.81 | GABRA5 (0.44) | ITGB3ITGA2BGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365693-A | Selected CGRP antagonists, method for the production thereof and use thereof as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2009-02-11 | — | — | CN | disclosed |
| CN-101273021-A | Selected CGRP antagonists, methods for the production thereof and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2008-09-24 | — | — | CN | disclosed |
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |