Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 11/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 10/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965007 | 0.78 | TPSAB1 (0.69) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7421494 | 0.76 | TPSAB1 (0.57) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7554479 | 0.75 | TPSAB1 (0.53) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7421119 | 0.73 | TPSG1 (0.69) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7419019 | 0.73 | MEN1 (0.52) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7424872 | 0.71 | TPSAB1 (0.53) | TPSAB1TPSG1TPSD1PRSS1F2 | |
| SCHEMBL7421440 | 0.70 | TPSG1 (0.71) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7415218 | 0.70 | TPSAB1 (0.77) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL7436458 | 0.70 | TPSAB1 (0.48) | TPSAB1TPSG1TPSD1PRSS1PLG | |
| SCHEMBL12431419 | 0.69 | TPSG1 (0.71) | TPSAB1TPSG1TPSD1PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782571-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-07-09 | — | — | EP | claimed |
| WO-1996009297-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-03-28 | — | — | WO | claimed |