Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423963 | 0.86 | OPRK1 (0.48) | CTSKCTSLCTSBCA1CTSS | |
| SCHEMBL7415842 | 0.80 | HSD17B10 (0.43) | CTSKCTSLCTSBCTSSL3MBTL1 | |
| SCHEMBL7429544 | 0.77 | LMNA (0.45) | CTSKCTSLCTSBCTSSL3MBTL1 | |
| SCHEMBL5869689 | 0.74 | CTSK (0.47) | CTSKCTSLCTSSATML3MBTL1 | |
| SCHEMBL5869683 | 0.74 | CTSK (0.47) | CTSKCTSLCTSSATML3MBTL1 | |
| SCHEMBL5869681 | 0.74 | CTSK (0.47) | CTSKCTSLCTSSATML3MBTL1 | |
| SCHEMBL7427243 | 0.74 | PPARA (0.45) | CTSKNPC1RAB9AATML3MBTL1 | |
| SCHEMBL7422349 | 0.73 | AAK1 (0.43) | CTSKCTSLCTSBCTSSL3MBTL1 | |
| SCHEMBL7421654 | 0.72 | PKM (0.45) | CTSLCTSBNPC1POLB | |
| SCHEMBL7418972 | 0.70 | CTSK (0.43) | CTSKCTSLCTSSATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |