Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414507 | 0.92 | NPY1R (0.32) | NPY1R | |
| SCHEMBL5778204 | 0.78 | HTR6 (0.42) | NPY1RCNR2IRAK4 | |
| SCHEMBL7655147 | 0.74 | CNR2 (0.45) | NPY1RCNR2CTNNB1IRAK4 | |
| SCHEMBL5776881 | 0.68 | ALDH1A1 (0.43) | NPY1RCNR2 | |
| SCHEMBL7429443 | 0.65 | MEN1 (0.45) | — | |
| SCHEMBL5774251 | 0.65 | ALDH1A1 (0.41) | NPY1RCNR2 | |
| SCHEMBL8944811 | 0.63 | MAPT (0.49) | — | |
| SCHEMBL16927639 | 0.62 | CHEK1 (0.55) | — | |
| SCHEMBL5401386 | 0.62 | TACR1 (0.48) | — | |
| SCHEMBL5408982 | 0.62 | TACR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200433-A1 | C-6 RING-SUBSTITUTED PYRIDO 1,2- i a /i ]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009132-A1 | C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-02-08 | — | — | WO | disclosed |