Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021951 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL139113 | 0.80 | CA6 (0.40) | ALDH1A1MAPTKDM4EL3MBTL1HSD17B10 | |
| SCHEMBL24716192 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL1129180 | 0.79 | HSD17B10 (0.48) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL1946105 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL741941 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL11378722 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL30193870 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL12056456 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL27728509 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704090-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4735534-A2 | BENZOTHIAZOLE DYES | Detect, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2026-01-22 | — | — | US | disclosed |
| EP-4623914-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| EP-4619388-A1 | CATHEPSIN L INHIBITORS | Biofront Therapeutics (Beijing) Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| US-20250206707-A1 | NOVEL COMPOUND INDUCING EXPRESSION OF ANTI-AGING GENE KLOTHO | KLOTHO SCIENCES CO., LTD. (KR) | 2025-06-26 | — | — | US | disclosed |
| CN-120035438-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20250115619-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2025-04-10 | — | — | US | disclosed |
| US-12227520-B2 | Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use | GILEAD SCIENCES, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| CN-119462659-A | Bridged tricyclic carbamoyl pyridone compounds and pharmaceutical uses thereof | 吉利德科学公司 | 2025-02-18 | — | — | CN | disclosed |
| US-7220738-B2 | Rifamycin analogs and uses thereof | ACTIVBIOTICS, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| EP-1773330-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2007039177-A2 | PHENYL- AND PYRIDINYL- 1, 2 , 4 - OXADIAZOLONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (DE) | 2007-04-12 | — | — | WO | disclosed |
| EP-1767530-A1 | BENZOXAZOLES | KYOYU AGRI CO., LTD (JP) | 2007-03-28 | — | — | EP | disclosed |
| EP-1697382-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | ActivBiotics, Inc. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2006068904-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| WO-2006014618-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20050209226-A1 | Neurodegenerative diseases, psychological disorders; e.g. 4-[3-(3a -Cyclopropylmethoxy-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-4H-benzo[1.4]oxazin-3-one | ACADIA PHARMACEUTICALS INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005058231-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | ACTIVBIOTICS, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050137189-A1 | Rifamycin analogs and uses thereof | ACTIVBIOTICS PHARMA LLC | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115619-A1 | BRIDGED TRICYCLIC CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE | ZYX, CCNY, NCAPD3 | ALDH1A1 1700/4885MAPT 1576/4885GAA 2473/4885 |
| US-20050209226-A1 | Neurodegenerative diseases, psychological disorders; e.g. 4-[3-(3a -Cyclopropylmethoxy-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-4H-benzo[1.4]oxazin-3-one | CHRNA4, CHRNA2, CHRNA5 | ALDH1A1 1911/4885MAPT 176/4885GAA 932/4885 |
| US-12227520-B2 | Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use | ZYX, CCNY, XDH | ALDH1A1 1782/4885MAPT 1709/4885GAA 2501/4885 |
| US-20250206707-A1 | NOVEL COMPOUND INDUCING EXPRESSION OF ANTI-AGING GENE KLOTHO | CTSA, ALDH1A2, KLHL20 | ALDH1A1 537/4885MAPT 2897/4885GAA 394/4885 |
| US-20050137189-A1 | Rifamycin analogs and uses thereof | RIF1, HDAC5, HDAC4 | ALDH1A1 873/4885MAPT 3678/4885GAA 219/4885 |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | NAMPT, NAPRT, NNT | ALDH1A1 789/4885MAPT 1402/4885GAA 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.