Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415584 | 0.80 | SMN1; SMN2 (0.78) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4182162 | 0.79 | KMT2A (0.77) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7420835 | 0.77 | PKM (0.65) | MAPK1HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL4609361 | 0.77 | ALDH1A1 (0.74) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL17235938 | 0.76 | MAPK1 (0.65) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7425542 | 0.76 | ALDH1A1 (0.69) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL15682790 | 0.75 | MAPK1 (0.58) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7423847 | 0.75 | SMN1; SMN2 (0.71) | MAPK1HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7425706 | 0.75 | SMN1; SMN2 (1.00) | MAPK1HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7420609 | 0.75 | HTT (0.78) | MAPK1HTTSMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |