Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | HTRA1 | Q92743 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421813 | 0.91 | MME (0.48) | MMEACECPA1ACE2HTRA1 | |
| SCHEMBL7414303 | 0.88 | CMA1 (0.52) | SMN1; SMN2ELANEMMEACECPA1 | |
| SCHEMBL8364492 | 0.88 | CTSD (0.48) | RENELANEPGA5 | |
| SCHEMBL8736216 | 0.84 | CTSD (0.53) | MMEACECPA1ACE2HTRA1 | |
| SCHEMBL7420852 | 0.82 | CMA1 (0.52) | RENTSHRPGA5ALDH1A1MME | |
| SCHEMBL7418725 | 0.81 | MME (0.46) | MMEACECPA1ACE2HTRA1 | |
| SCHEMBL7418157 | 0.81 | REN (0.45) | RENELANEPGA5MMEACE | |
| SCHEMBL7423864 | 0.81 | REN (0.45) | RENELANEPGA5MMEACE | |
| SCHEMBL7416869 | 0.80 | MME (0.43) | RENMMEACECPA1ACE2 | |
| SCHEMBL8945318 | 0.80 | CTSD (0.46) | MMEACECPA1ACE2HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | claimed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | claimed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |