Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | HTRA1 | Q92743 | 8/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806325 | 0.94 | CMA1 (0.49) | CTSDCMA1CTSSCTSKHTRA1 | |
| SCHEMBL8736216 | 0.91 | CTSD (0.53) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL8041651 | 0.88 | MME (0.47) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL8945610 | 0.86 | MME (0.45) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL7416869 | 0.86 | MME (0.43) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL7422223 | 0.85 | ITGB3 (0.45) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL8364492 | 0.85 | CTSD (0.48) | CTSDCMA1 | |
| SCHEMBL7933938 | 0.85 | CTSD (0.47) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL8945566 | 0.85 | CTSD (0.47) | CTSDCMA1CTSSCTSKMME | |
| SCHEMBL8945567 | 0.85 | CTSD (0.53) | CTSDCTSSCTSKITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |