Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424015 | 0.86 | GPR88 (0.42) | MMP2CTSKGPR88F7CTSL | |
| SCHEMBL7424891 | 0.84 | PTGS2 (0.43) | MMP2MMP3PTGESGPR88ERAP2 | |
| SCHEMBL7422595 | 0.83 | RXRA (0.40) | PTGESERAP2ERAP1LNPEPF7 | |
| SCHEMBL7428411 | 0.81 | CYP1A1 (0.40) | PTGESCTSKGPR88HTR1A | |
| SCHEMBL7378945 | 0.79 | MEN1 (0.48) | MMP2MMP3 | |
| SCHEMBL7421681 | 0.77 | ALDH1A1 (0.35) | CTSKGPR88CTSLCTSBCTSS | |
| SCHEMBL7419980 | 0.75 | AOC3 (0.46) | SLC6A9 | |
| SCHEMBL5869134 | 0.75 | FOLH1 (0.49) | MMP2MMP3PRMT6CTSKHTR1A | |
| SCHEMBL5869139 | 0.75 | FOLH1 (0.49) | MMP2MMP3PRMT6CTSKHTR1A | |
| SCHEMBL5869128 | 0.75 | FOLH1 (0.49) | MMP2MMP3PRMT6CTSKHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |