Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420946 | 0.86 | MMP2 (0.46) | GPR88CTSLCTSBCTSSCTSK | |
| SCHEMBL7424796 | 0.85 | HPGD (0.38) | GPR88MMEF7MCHR1MMP8 | |
| SCHEMBL7420384 | 0.84 | MMP12 (0.46) | GPR88CTSLCTSBCTSSCTSK | |
| SCHEMBL7425601 | 0.84 | MCHR1 (0.50) | GPR88MMEMCHR1MMP2 | |
| SCHEMBL7427409 | 0.84 | MMP12 (0.46) | GPR88CTSLCTSBCTSSCTSK | |
| SCHEMBL7421681 | 0.81 | ALDH1A1 (0.35) | GPR88CTSLCTSBCTSSCTSK | |
| SCHEMBL7418362 | 0.81 | PSEN1 (0.51) | MMP2MMP9 | |
| SCHEMBL7419478 | 0.81 | MMP2 (0.42) | MMEF7MCHR1MMP2 | |
| SCHEMBL7417897 | 0.80 | FOLH1 (0.45) | MMEMMP8 | |
| SCHEMBL7378945 | 0.80 | MEN1 (0.48) | MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |