Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.45 |
| ▸ | CTSS | P25774 | 11/20 | 0.45 |
| ▸ | CTSL | P07711 | 9/20 | 0.45 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424022 | 0.87 | CTSS (0.51) | CTSKCTSSCTSLCTSBMMP2 | |
| SCHEMBL7424899 | 0.83 | CTSK (0.50) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7422599 | 0.82 | GRN (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7428422 | 0.80 | AKR1C3 (0.45) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7378949 | 0.79 | MME (0.50) | CTSKCTSS | |
| SCHEMBL7421684 | 0.78 | S1PR4 (0.40) | CTSKCTSSCTSLCTSBMMP2 | |
| SCHEMBL7421831 | 0.77 | NTSR1 (0.54) | CTSKCTSSCTSL | |
| SCHEMBL5869139 | 0.75 | FOLH1 (0.49) | CTSKCTSSCTSLCTSBPRMT6 | |
| SCHEMBL7420340 | 0.75 | MAPT (0.44) | CTSKCTSSCTSL | |
| SCHEMBL5869134 | 0.75 | FOLH1 (0.49) | CTSKCTSSCTSLCTSBPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |