Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313888 | 0.83 | LIPE (0.39) | LIPEMCHR1KDM4EALDH1A1ENPP2 | |
| SCHEMBL9893746 | 0.76 | LIPE (0.63) | LIPEENPP2 | |
| SCHEMBL3465794 | 0.75 | ENPP2 (0.56) | LIPEKDM4EALDH1A1ENPP2 | |
| SCHEMBL9893638 | 0.73 | PTGS2 (0.41) | KDM4EALDH1A1ENPP2 | |
| SCHEMBL3825559 | 0.72 | ENPP2 (0.36) | LIPEALDH1A1ENPP2 | |
| SCHEMBL9893573 | 0.71 | KEAP1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL2385935 | 0.71 | LMNA (0.38) | ALDH1A1ENPP2 | |
| SCHEMBL840950 | 0.70 | ENPP2 (0.32) | ALDH1A1ENPP2 | |
| SCHEMBL9893413 | 0.70 | ELANE (0.37) | KDM4EENPP2 | |
| SCHEMBL5899432 | 0.70 | TSHR (0.36) | KDM4EALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057273-A1 | SERINE PROTEASE INHIBITORS COMPRISING A HYDROGEN-BOND ACCEPTOR | TRIGEN LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |