Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418770 | 0.87 | MTNR1A (0.47) | MTNR1AMTNR1BDAOKDM4ETSHR | |
| SCHEMBL7469548 | 0.86 | KDM4E (0.42) | MTNR1AMTNR1BDAOKDM4ETSHR | |
| SCHEMBL7418610 | 0.82 | PPARG (0.48) | MTNR1AMTNR1BDAOKDM4ETSHR | |
| SCHEMBL10646766 | 0.81 | KDM4E (0.47) | MTNR1AMTNR1BDAOITKKDM4E | |
| SCHEMBL7417442 | 0.75 | MTNR1A (0.41) | MTNR1AMTNR1BTSHRKDM5AKDM5B | |
| SCHEMBL5981755 | 0.71 | CASP3 (0.51) | MTNR1AMTNR1BITKKDM4EALDH1A1 | |
| SCHEMBL7420510 | 0.70 | KMT2A (0.53) | MTNR1AMTNR1BKDM4EALDH1A1MEN1 | |
| SCHEMBL16729160 | 0.69 | ALOX15 (0.52) | DAOKDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL27475142 | 0.68 | MAPT (0.51) | DAOITKKDM4ETSHRALDH1A1 | |
| SCHEMBL8555547 | 0.68 | MTNR1A (0.46) | MTNR1AMTNR1BKDM4ETSHRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996032379-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-17 | — | — | WO | disclosed |